Lutetium Therapy: Palliative treatment for people with advanced prostate cancer
For patients with advanced prostate cancer, your oncologist may refer you for Lutetium-177 PSMA therapy.
This innovative treatment option is most suitable for patients with advanced prostate cancer who have failed other forms of treatment such as hormone therapy or chemotherapy.
Before commencing treatment, patients will undergo a PSMA PET-CT scan to locate the PSMA receptors on the cancer cells. PSMA (Prostate Specific Membrane Antigen) is a cell membrane protein with enzymatic activity that is highly expressed in prostate cancer cell but not on normal prostate tissue or benign lesions.
Lutetium is a low-level radiation substance that destroys nearby cells. We combine this with a PSMA protein that specifically seeks out and targets PSMA receptors.
It is injected into the bloodstream which takes around 30 minutes every 6-8 weeks. Most patients require four treatment cycles.
Over time, it will destroy prostate cancer cells, including those that have spread into other parts of the body.